The JAK-STAT pathway in Drosophila

被引：54
作者：
Hou, XS
Perrimon, N
机构：
[1] Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston
来源：
TRENDS IN GENETICS | 1997年 / 13卷 / 03期
关键词：
D O I：
10.1016/S0168-9525(97)01006-8
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Recent studies in Drosophila have identified a single JAK and a single STAT protein. Genetic and biochemical analyses reveal that these two proteins operate in the same signal transduction pathway. phenotypic analyses of JAK and STAT mutants implicate this pathway in a number of developmental decisions, in particular the regulation of pair-rule genes and fly hematopoiesis.
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页码：105 / 110
页数：6
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