The treatment of a thyrotropin-secreting pituitary macroadenoma with octreotide in twin pregnancy

被引:23
作者
Blackhurst, G [1 ]
Strachan, MW [1 ]
Collie, D [1 ]
Gregor, A [1 ]
Statham, PFX [1 ]
Seckl, JER [1 ]
机构
[1] Univ Edinburgh, Mol Med Ctr, Endocrinol Unit, Edinburgh EH4 2XU, Midlothian, Scotland
关键词
D O I
10.1046/j.1365-2265.2002.01549.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
TSH-secreting pituitary tumours are rare but difficult to treat due to a combination of refractory hyperthyroidism and low surgical cure rates. We describe the case of a 21-year-old woman who, despite twin pregnancy, became euthyroid and had dramatic tumour shrinkage on octreotide treatment. To our knowledge, this is the first description of the use of octreotide for a TSH-secreting pituitary adenoma throughout pregnancy.
引用
收藏
页码:401 / 404
页数:4
相关论文
共 15 条
[1]   Thyrotropin-secreting pituitary tumors [J].
BeckPeccoz, P ;
BruckerDavis, F ;
Persani, L ;
Smallridge, RC ;
Weintraub, BD .
ENDOCRINE REVIEWS, 1996, 17 (06) :610-638
[2]   Thyrotropin-secreting pituitary tumors: Diagnostic criteria, thyroid hormone sensitivity, and treatment outcome in 25 patients followed at the national institutes of health [J].
Brucker-Davis, F ;
Oldfield, EH ;
Skarulis, MC ;
Doppman, JL ;
Weintraub, BD .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (02) :476-486
[3]   Expression of somatostatin receptor SST4 in human placenta and absence of octreotide effect on human placental growth hormone concentration during pregnancy [J].
Caron, P ;
Buscail, L ;
Beckers, A ;
Esteve, JP ;
Igout, A ;
Hennen, G ;
Susini, C .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (11) :3771-3776
[4]   Successful pregnancy in an infertile woman with a thyrotropin-secreting macroadenoma treated with somatostatin analog (octreotide) [J].
Caron, P ;
Gerbeau, C ;
Pradayrol, L ;
Simonetta, C ;
Bayard, F .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1996, 81 (03) :1164-1168
[5]   OCTREOTIDE THERAPY FOR THYROID-STIMULATING HORMONE-SECRETING PITUITARY-ADENOMAS - A FOLLOW-UP OF 52 PATIENTS [J].
CHANSON, P ;
WEINTRAUB, BD ;
HARRIS, AG .
ANNALS OF INTERNAL MEDICINE, 1993, 119 (03) :236-240
[6]   Diagnosis and treatment of pituitary tumors [J].
Freda, PU ;
Wardlaw, SL .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (11) :3859-3866
[7]  
GANCEL A, 1994, CLIN ENDOCRINOL, V40, P421
[8]   PITUITARY-GLAND GROWTH DURING NORMAL-PREGNANCY - AN INVIVO STUDY USING MAGNETIC-RESONANCE IMAGING [J].
GONZALEZ, JG ;
ELIZONDO, G ;
SALDIVAR, D ;
NANEZ, H ;
TODD, LE ;
VILLARREAL, JZ .
AMERICAN JOURNAL OF MEDICINE, 1988, 85 (02) :217-220
[9]   Pregnancy in acromegaly: Successful therapeutic outcome [J].
Herman-Bonert, V ;
Seliverstov, M ;
Melmed, S .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1998, 83 (03) :727-731
[10]   Familial dysalbuminemic hyperthyroxinemia in a Swiss family caused by a mutant albumin (R218P) shows an apparent discrepancy between serum concentration and affinity for thyroxine [J].
Pannain, S ;
Feldman, M ;
Eiholzer, U ;
Weiss, RE ;
Scherberg, NH ;
Refetoff, S .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2000, 85 (08) :2786-2792