Monoterpenoid Coumarins from the Peels of Clausena lansium

被引:17
作者
Deng, Hui-Dong [1 ,2 ]
Mei, Wen-Li [1 ]
Guo, Zhi-Kai [1 ]
Liu, Shuai [1 ]
Zuo, Wen-Jian [1 ]
Dong, Wen-Hua [1 ]
Li, Shao-Peng [2 ]
Dai, Hao-Fu [1 ]
机构
[1] Chinese Acad Trop Agr Sci, Key Lab Biol & Genet Resources Trop Crops, Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Minist Agr,Inst Trop Biosci & Biotechnol, Haikou 571101, Hainan, Peoples R China
[2] Hainan Univ, Coll Hort & Landscape Architecture, Minist Educ, Key Lab Protect & Dev Utilizat Trop Crop Germplas, Haikou 570228, Hainan, Peoples R China
关键词
Clausena lansium; Rutaceae; monoterpenoid coumarins; clauslactone V; clauslactone W; hypoglycemic activity; CARBAZOLE ALKALOIDS; CONSTITUENTS; LEAVES;
D O I
10.1055/s-0034-1382839
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A phytochemical investigation on the peels of Clausena lansium (Lour.) Skeels led to the isolation of two new monoterpenoid coumarins, named clauslactone V (1) and clauslactone W (2), together with three known analogues (3-5). Their structures were elucidated by spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). All the compounds were evaluated for hypoglycemic activity, and compounds 1-5 showed alpha-glucosidase inhibitory activity in vitro.
引用
收藏
页码:955 / 958
页数:4
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