Monitoring cerebral blood flow change through use of arterial spin labelling in acute ischaemic stroke patients after intra-arterial thrombectomy

被引：17

作者：

Yoo, Roh-Eul ^{[1
,2
]}

Yun, Tae Jin ^{[1
,2
]}

Yoo, Dong Hyun ^{[1
,2
]}

Cho, Young Dae ^{[1
,2
]}

Kang, Hyun-Seung ^{[3
]}

Yoon, Byung-Woo ^{[4
]}

Jung, Keun-Hwa ^{[4
]}

Kang, Koung Mi ^{[1
,2
]}

Choi, Seung Hong ^{[1
,2
]}

Kim, Ji-hoon ^{[1
,2
]}

Sohn, Chul-Ho ^{[1
,2
]}

机构：

[1] Seoul Natl Univ, Med Res Ctr, Inst Radiat Med, Seoul, South Korea

[2] Seoul Natl Univ Hosp, Dept Radiol, 101 Daehangno, Seoul 110744, South Korea

[3] Seoul Natl Univ Hosp, Dept Neurosurg, Seoul, South Korea

[4] Seoul Natl Univ Hosp, Dept Neurol, Seoul, South Korea

来源：

EUROPEAN RADIOLOGY | 2018年 / 28卷 / 08期

关键词：

Perfusion; Prognosis; Reperfusion; Stroke; Thrombectomy; CONSENSUS STATEMENT; PERFUSION MRI; TUMORS; TRIAL;

D O I：

10.1007/s00330-018-5319-0

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

To evaluate the ability of arterial spin labelling perfusion-weighted imaging (ASL-PWI) to identify reperfusion status and to predict the early neurological outcome of acute ischaemic stroke patients after intra-arterial (IA) thrombectomy. A total of 51 acute ischaemic stroke patients who underwent IA thrombectomy were retrospectively reviewed. Asymmetrical index before and after IA thrombectomy (AICBF(pre) and AICBF(post)) and volume ratio of the reperfused territory to the baseline perfusion abnormality (reperfusion volume ratio) were calculated on ASL-PWI. A paired t-test was used to compare AICBF(pre) and AICBF(post). Pearson correlation and multiple linear regression were performed to evaluate correlations between the imaging parameters and NIHSS scores. Mean AICBF(post) was significantly higher than mean AICBF(pre) (0.923 +/- 0.352 vs. 0.312 +/- 0.191, p < 0.001). AICBF(pre) had a significant correlation with NIHSSpre (pr=-0.430, p=.004). a dagger AICBF had significant correlations with NIHSS24 h, NIHSS5-7 days and a dagger NIHSS5-7 days (r=-0.356, p=0.028; r=-0.597, p < 0.001; r=-0.346, p=0.033, respectively). a dagger AICBF, reperfusion volume ratio and baseline infarct volume were significant independent predictors for NIHSS5-7 days. ASL-PWI has the potential to serve as a non-invasive imaging tool to monitor the reperfusion status and predict the early neurological outcome of acute ischaemic stroke patients after IA thrombectomy. aEuro cent CBF change on ASL-PWI after IA thrombectomy correlated with NIHSS scores. aEuro cent ASL-PWI can non-invasively monitor reperfusion in AIS patients after IA thrombectomy. aEuro cent ASL-PWI may predict early outcome of AIS patients after IA thrombectomy.

引用

页码：3276 / 3284

页数：9

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