Elastic rod model of a DNA loop in the lac operon

被引：70

作者：

Balaeff, A ^{[1
]}

Mahadevan, L

Schulten, K

机构：

[1] Univ Illinois, Beckman Inst, Urbana, IL 61801 USA

[2] Univ Illinois, Ctr Biophys & Computat Biol, Urbana, IL 61801 USA

[3] MIT, Dept Mech Engn, Cambridge, MA 02139 USA

[4] Univ Illinois, Dept Phys, Urbana, IL 61801 USA

来源：

PHYSICAL REVIEW LETTERS | 1999年 / 83卷 / 23期

关键词：

D O I：

10.1103/PhysRevLett.83.4900

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We use the theory of elasticity to compute the shape of the DNA loop bridging the gap in the crystal structure of the lac repressor-DNA complex. The Kirchhoff system of equations with boundary conditions derived from the crystal structure is solved using a continuation method. This approach can be applied effectively to find coarse-grained conformational minima of DNA loops.

引用

页码：4900 / 4903

页数：4

共 31 条

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[2]

[Anonymous], 1996, MOL MODELING

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