Total synthesis of mansonone E

被引：2

作者：

Fang, Xianhe ^{[1
]}

Hu, Xiangdong ^{[1
]}

机构：

[1] NW Univ Xian, Dept Chem & Mat Sci, Key Lab Synthet & Nat, Funct Mol Chem Minist Educ China, Xian 710069, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2014年 / 03期

基金：

中国国家自然科学基金;

关键词：

total synthesis; natural products; ring expansion; cyclisation; quinones; REGIOSPECIFIC SYNTHESIS; SESQUITERPENES; CYCLOBUTENEDIONES; COMPLEXES; BENZYNES;

D O I：

10.3184/174751914X13899760861508

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of mansonone E was completed in six steps and 34% overall yield from commercially available starting material 3-bromo-4-methyl acetophenone. The thermal ring expansion of a cyclobutenedione derivative followed by an intramolecular 1,3-alkoxy exchange provided a facile route to the 1,2-naphthoquinone tricyclic structure of mansonone E.

引用

页码：137 / 139

页数：3

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