Zebrafish as a cancer model system

被引:291
作者
Amatruda, JF
Shepard, JL
Stern, HM
Zon, LI [1 ]
机构
[1] Childrens Hosp, Howard Hughes Med Inst, Dept Hematol Oncol, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Dept Pathol, Boston, MA 02115 USA
关键词
D O I
10.1016/S1535-6108(02)00052-1
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The zebrafish, with its combination of forward genetics and vertebrate biology, has great potential as a cancer model system.
引用
收藏
页码:229 / 231
页数:3
相关论文
共 10 条
[1]   A large-scale insertional mutagenesis screen in zebrafish [J].
Amsterdam, A ;
Burgess, S ;
Golling, G ;
Chen, WB ;
Sun, ZX ;
Townsend, K ;
Farrington, S ;
Haldi, M ;
Hopkins, N .
GENES & DEVELOPMENT, 1999, 13 (20) :2713-2724
[2]  
Driever W, 1996, DEVELOPMENT, V123, P37
[3]  
Haffter P, 1996, DEVELOPMENT, V123, P1
[4]   DEVELOPMENT OF AQUARIUM FISH MODELS FOR ENVIRONMENTAL CARCINOGENESIS - TUMOR-INDUCTION IN 7 SPECIES [J].
HAWKINS, WE ;
OVERSTREET, RM ;
FOURNIE, JW ;
WALKER, WW .
JOURNAL OF APPLIED TOXICOLOGY, 1985, 5 (04) :261-264
[5]  
Nasevicius A, 2001, CURR OPIN MOL THER, V3, P224
[6]   The art and design of genetic screens: Zebrafish [J].
Patton, EE ;
Zon, LI .
NATURE REVIEWS GENETICS, 2001, 2 (12) :956-966
[7]   Small molecule developmental screens reveal the logic and timing of vertebrate development [J].
Peterson, RT ;
Link, BA ;
Dowling, JE ;
Schreiber, SL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (24) :12965-12969
[8]   Neoplasia in zebrafish (Danio rerio) treated with 7,12-dimethylbenz[a]anthracene by two exposure routes at different developmental stages [J].
Spitsbergen, JM ;
Tsai, HW ;
Reddy, A ;
Miller, T ;
Arbogast, D ;
Hendricks, JD ;
Bailey, GS .
TOXICOLOGIC PATHOLOGY, 2000, 28 (05) :705-715
[9]   Technologically advanced cancer modeling in mice [J].
Tuveson, DA ;
Jacks, T .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 2002, 12 (01) :105-110
[10]  
Walter R B, 2001, ILAR J, V42, P299