Colorimetric detection of human chorionic gonadotropin using catalytic gold nanoparticles and a peptide aptamer

被引:53
|
作者
Chang, Chia-Chen [1 ]
Chen, Chie-Pein [2 ]
Lee, Chung-Han [1 ]
Chen, Chen-Yu [2 ,3 ,4 ]
Lin, Chii-Wann [1 ,5 ,6 ]
机构
[1] Natl Taiwan Univ, Inst Biomed Engn, Taipei 106, Taiwan
[2] Mackay Mem Hosp, Dept Obstet & Gynecol, Taipei 104, Taiwan
[3] Mackay Jr Coll Med Nursing & Management, Taipei 112, Taiwan
[4] Mackay Med Coll, Taipei 252, Taiwan
[5] Natl Taiwan Univ, Inst Biomed Elect & Bioinformat, Taipei 106, Taiwan
[6] Natl Taiwan Univ, Ctr Emerging Mat & Adv Devices, Taipei 106, Taiwan
关键词
GERM-CELL TUMORS; AMPEROMETRIC IMMUNOSENSOR; PROTEIN BIOMARKERS; ECTOPIC PREGNANCY; HCG; FLUIDS; ASSAY; EXPERIENCE; DIAGNOSIS; GRAPHENE;
D O I
10.1039/c4cc06366j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We combined catalytic gold nanoparticles (AuNPs) with an hCG-specific peptide aptamer to create a simple, sensitive, label-free colorimetric assay for hCG. The applications of this colorimetric biosensor may be expanded by changing the peptide aptamer.
引用
收藏
页码:14443 / 14446
页数:4
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