Transition metal free synthesis of 2,4,6-trisubstituted pyrimidines via Cope-type hydroamination of 1,4-diarylbuta-1,3-diynes

被引：13
作者：
Singha, Raju [1 ]
Ray, Jayanta K. [1 ]
机构：
[1] Indian Inst Technol, Dept Chem, Kharagpur 721302, W Bengal, India
来源：
RSC ADVANCES | 2014年 / 4卷 / 83期
关键词：
ALKYNES; 1,3-DIALKYNES; DERIVATIVES; NITRILES; ACID;
D O I：
10.1039/c4ra07690g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We have developed an efficient and transition metal free methodology for the synthesis of 2,4,6-trisubstituted pyrimidines by the Cope-type hydroamination reaction of 1,4-diarylbuta-1,3-diynes with amidines in DMSO solvent.
引用
收藏
页码：44052 / 44055
页数：4
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