Brain plasticity-based therapeutics

被引：134

作者：

Merzenich, Michael M. ^{[1
]}

Van Vleet, Thomas M. ^{[1
,2
]}

Nahum, Mor ^{[1
,3
]}

机构：

[1] Posit Sci Corp, San Francisco, CA 94108 USA

[2] Dept Vet Affairs, Martinez, CA USA

[3] Univ Calif Berkeley, Dept Optometry, Berkeley, CA 94720 USA

来源：

FRONTIERS IN HUMAN NEUROSCIENCE | 2014年 / 8卷

关键词：

brain plasticity; neuroplasticity; computerized training; aging; hemispatial neglect; schizophrenia; AUDITORY SUSTAINED ATTENTION; LOCUS-COERULEUS; NEUROCOGNITIVE DEFICITS; ALZHEIMERS-DISEASE; SOCIAL COGNITION; SPATIAL NEGLECT; ANTIPSYCHOTIC MEDICATIONS; DEPENDENT PLASTICITY; REVERSE HIERARCHIES; CORTICAL PLASTICITY;

D O I：

10.3389/fnhum.2014.00385

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The primary objective of this review article is to summarize how the neuroscience of brain plasticity, exploiting new findings in fundamental, integrative and cognitive neuroscience, is changing the therapeutic landscape for professional communities addressing brain-based disorders and disease. After considering the neurological bases of training driven neuroplasticity, we shall describe how this neuroscience-guided perspective distinguishes this new approach from (a) the more-behavioral, traditional clinical strategies of professional therapy practitioners, and (b) an even more widely applied pharmaceutical treatment model for neurological and psychiatric treatment domains. With that background, we shall argue that neuroplasticity-based treatments will be an important part of future best-treatment practices in neurological and psychiatric medicine.

引用

页数：16

共 160 条

[1] When Top-Down Meets Bottom-Up: Auditory Training Enhances Verbal Memory in Schizophrenia [J].