Long-Term Effects of Kasai Portoenterostomy for Biliary Atresia Treatment in Russia

被引：8

作者：

Degtyareva, Anna ^{[1
,2
]}

Razumovskiy, Alexander ^{[3
,4
]}

Kulikova, Nadezhda ^{[4
]}

Ratnikov, Sergey ^{[5
]}

Filippova, Elena ^{[1
]}

Gordeeva, Ekaterina ^{[4
]}

Albegova, Marina ^{[1
]}

Rebrikov, Denis ^{[1
,3
]}

Puchkova, Anna ^{[1
]}

机构：

[1] Kulakov Natl Med Res Ctr Obstet Gynecol & Perinat, 4 Oparina St, Moscow 117997, Russia

[2] Sechenov Univ, Neonatol Dept, 8 Trubetskaya St, Moscow 119991, Russia

[3] Pirogov Russian Natl Res Med Univ, Ctr Precis Genome Editing & Genet Technol Biomed, 1 Ostrovityanova St, Moscow 117997, Russia

[4] Filatov Munitsipal Childrens Hosp, 15 Sadovaya Kudrinskaya St, Moscow 123001, Russia

[5] Natl Med Res Ctr Childrens Hlth, 2 Lomonosovsky Prospect, Moscow 119296, Russia

来源：

DIAGNOSTICS | 2020年 / 10卷 / 09期

关键词：

biliary atresia; Kasai portoenterostomy; cholangitis; portal hypertension; bile ducts dilatations; native liver survival; CHOLANGITIS; EXPERIENCE; MANAGEMENT; OPERATION; OUTCOMES; CHILDREN;

D O I：

10.3390/diagnostics10090686

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This prospective study enrolled 144 patients after surgical treatment of biliary atresia in early infancy. We analyzed the immediate effectiveness of the surgery and the age-related structure of complications in the up to 16-year follow-up. The immediate 2-year survival rate after the surgery constituted 49.5%. At the time of this writing, 17 of the patients had celebrated their 10th birthdays with good quality of life and no indications for transplantation of the liver. The obtained results underscore the critical importance of surgical correction of biliary atresia by Kasai surgery in the first 60 days of life and subsequent dynamic follow-up of patients for the purpose of the early detection and timely correction of possible complications.

引用

页数：13

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