Immune therapy for pharmacoresistant epilepsy Ready to go?

被引：8

作者：

Rueegg, Stephan ^{[1
]}

Panzer, Jessica A. ^{[2
,3
]}

机构：

[1] Univ Basel Hosp, Dept Neurol, Div Clin Neurophysiol, Basel, Switzerland

[2] Childrens Hosp Philadelphia, Div Neurol, Philadelphia, PA USA

[3] Univ Penn, Perelman Sch Med, Hosp Univ Penn, Philadelphia, PA 19104 USA

来源：

NEUROLOGY | 2014年 / 82卷 / 18期

关键词：

RASMUSSENS ENCEPHALITIS; RECEPTOR ENCEPHALITIS; AUTOANTIBODIES;

D O I：

10.1212/WNL.0000000000000391

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Despite the introduction of almost 20 new antiseizure drugs in the last several decades, approximately 30% of patients with epilepsy have pharmacoresistant seizures. Although many genetic disorders and cerebral structural lesions are known causes of difficult-to-treat epilepsy, some refractory patients do not fall into these categories. In the search for other etiologic factors, the multiple and close interactions between the immune system and epilepsy have gained substantial interest.(1</SUP)

引用

页码：1572 / 1573

页数：2

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