Implementation of Quantitative Perfusion Imaging Using Pulsed Arterial Spin Labeling at Ultra-High Field

被引：40

作者：

Gardener, A. G. ^{[1
]}

Gowland, P. A. ^{[1
]}

Francis, S. T. ^{[1
]}

机构：

[1] Univ Nottingham, Sir Peter Mansfield Magnet Resonance Ctr, Sch Phys & Astron, Nottingham NG7 2RD, England

来源：

MAGNETIC RESONANCE IN MEDICINE | 2009年 / 61卷 / 04期

基金：

英国工程与自然科学研究理事会;

关键词：

perfusion imaging; ASL; ultra-high field; quantification; optimization; CEREBRAL-BLOOD-FLOW; RELAXATION-TIME T-1; PHYSIOLOGICAL NOISE; FAIR TECHNIQUE; HUMAN BRAIN; OPTIMIZATION; PROFILE; SIGNAL; EXCITATION; MRI;

D O I：

10.1002/mrm.21796

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

This study compares the implementation of the STAR and FAIR pulsed arterial spin labeling (PASL) schemes to form quantitative perfusion maps at ultra-high field, 7 Tesla (T), and high field, 3T. Phantom experiments were performed to compare the inversion efficiency and profile of the labeling pulses at 7T and 3T and to optimize in-plane saturation techniques. The perfusion weighted (PW) signal was measured at a range of postlabeling delay times and quantitative perfusion maps were calculated on a voxel-by-voxel basis. An increase in PW signal was found with field strength, and together with the increased signal-to-noise ratio, this led to improved image signal-to-noise and quality of fit of perfusion maps at 7T. Magn Reson Med 61:874-882, 2009. (C) 2009 Wiley-Liss, Inc.

引用

页码：874 / 882

页数：9

共 36 条

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