Clinical and morphological characteristics of lupus nephritis in systemic lupus erythematosus with antiphospholipid syndrome

被引：0

作者：

Kozlovskaya, N. L. ^{[1
]}

Shilov, E. M. ^{[1
]}

Meteleva, N. A. ^{[1
]}

Varshavsky, V. A. ^{[1
]}

Miroshnichenko, N. G. ^{[1
]}

Samokishina, N. A. ^{[1
]}

Serova, A. G. ^{[1
]}

Nesterova, S. G. ^{[1
]}

机构：

[1] Sechenov Moscow Med Univ, Moscow, Russia

来源：

TERAPEVTICHESKII ARKHIV | 2006年 / 78卷 / 05期

关键词：

lupus nephritis; APS; APS-associated nephropathy; thrombotic microangiopathy;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim. To ascertain clinical and morphological features of lupus nephritis (LN) in systemic lupus erythematosus (SLE) associated with antiphospholipid syndrome (APS). Material and methods. Immunological markers of SLE and APS, clinical picture, urine indices were examined in 138 patients with SLE, APS and renal dysfunction. Results. LN associated with APS is characterized with marked arterial hypertension, such patients had arterial thromboses more frequently than patients with isolated LN. Patients with anticardiolipin antibodies have arteriolosclerosis, in APS - diffuse interstitial sclerosis. Conclusion. Renal impairment in SLE may run not only with LN but also with thrombotic microangiopathy modifying clinical symptoms and course of the disease.

引用

页码：21 / 31

页数：11

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