Ball Milling Promoted N-Heterocycles Synthesis

被引：32
作者：
El-Sayed, Taghreed H. [1 ,2 ]
Aboelnaga, Asmaa [1 ,2 ]
El-Atawy, Mohamed A. [1 ,3 ]
Hagar, Mohamed [1 ,3 ]
机构：
[1] Taibah Univ, Fac Sci, Chem Dept, Yanbu 46423, Saudi Arabia
[2] Ain Shams Univ, Fac Women Arts Sci & Educ, Chem Dept, Cairo 11757, Egypt
[3] Alexandria Univ, Fac Sci, Chem Dept, PO 426 Ibrahemia, Alexandria 21321, Egypt
来源：
MOLECULES | 2018年 / 23卷 / 06期
关键词：
ball milling; green synthesis; mechanochemistry; N-heterocycles; ONE-POT SYNTHESIS; SOLID-STATE SYNTHESES; SOLVENT-FREE; CASCADE REACTIONS; IN-VITRO; DERIVATIVES; ACID; MECHANOCHEMISTRY; ACTIVATION; CATALYST;
D O I：
10.3390/molecules23061348
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In the last years, numerous protocols have been published using ball milling for organic synthesis. Compared to other methods such as microwave or ultrasound irradiation and ionic liquids, ball mill chemistry is an economical, and ecofriendly method in organic synthesis that is rather underrepresented in the knowledge of organic chemists. The aim of this review is to explore the advantages of the application of ball milling in synthesis of N-heterocyclic compounds.
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页数：21
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