Phosphotungstic acid catalysed one-pot synthesis of 5-alkoxycarbonyl-4-aryl-3,4-dihydropyrimidin-2-ones

被引:0
作者
Jin, TS [1 ]
Xiao, JC [1 ]
Chen, YX [1 ]
Li, TS [1 ]
机构
[1] Hebei Univ, Coll Chem & Environm Sci, Dept Chem, Baoding 071002, Peoples R China
关键词
Biginelli reaction; dihydropyrimidinones; phosphotungstic acid; synthesis;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
5-Alkoxycarbonyl-4-aryl-3,4-dihydropyrimidin-2-ones are synthesised by the one-pot reactions of aldehydes, beta-ketoesters and urea using a catalytic amount of phosphotungstic acid (PTA) in ethanol. The modified Biginelli cyclocondensation not only shortens the reaction period and simplifies the operation, but also improves the yields.
引用
收藏
页码:190 / 191
页数:2
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