Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants

被引：16
|
作者：
Xin, Huhu [1 ]
Wan, Tao [1 ]
Ping, Yuan [1 ]
机构：
[1] Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310058, Zhejiang, Peoples R China
来源：
SIGNAL TRANSDUCTION AND TARGETED THERAPY | 2019年 / 4卷 / 1期
关键词：
GENOMIC DNA;
D O I：
10.1038/s41392-019-0044-y
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：2
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