A stochastic SIR network epidemic model with preventive dropping of edges

被引:23
作者
Ball, Frank [1 ]
Britton, Tom [2 ]
Leung, Ka Yin [2 ]
Sirl, David [1 ]
机构
[1] Univ Nottingham, Sch Math Sci, Univ Pk, Nottingham NG7 2RD, England
[2] Stockholm Univ, Dept Math, S-10691 Stockholm, Sweden
基金
瑞典研究理事会; 英国工程与自然科学研究理事会;
关键词
SIR epidemic; Configuration model; Social distancing; Density dependent population process; Effective degree; Final size; LARGE GRAPH LIMIT; LARGE NUMBERS; POPULATION; THEOREMS; VARIANCE; DYNAMICS; LAW;
D O I
10.1007/s00285-019-01329-4
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A Markovian Susceptible Infectious Recovered (SIR) model is considered for the spread of an epidemic on a configuration model network, in which susceptible individuals may take preventive measures by dropping edges to infectious neighbours. An effective degree formulation of the model is used in conjunction with the theory of density dependent population processes to obtain a law of large numbers and a functional central limit theorem for the epidemic as the population size N, assuming that the degrees of individuals are bounded. A central limit theorem is conjectured for the final size of the epidemic. The results are obtained for both the Molloy-Reed (in which the degrees of individuals are deterministic) and Newman-Strogatz-Watts (in which the degrees of individuals are independent and identically distributed) versions of the configuration model. The two versions yield the same limiting deterministic model but the asymptotic variances in the central limit theorems are greater in the Newman-Strogatz-Watts version. The basic reproduction number R0 and the process of susceptible individuals in the limiting deterministic model, for the model with dropping of edges, are the same as for a corresponding SIR model without dropping of edges but an increased recovery rate, though, when R0>1, the probability of a major outbreak is greater in the model with dropping of edges. The results are specialised to the model without dropping of edges to yield conjectured central limit theorems for the final size of Markovian SIR epidemics on configuration-model networks, and for the size of the giant components of those networks. The theory is illustrated by numerical studies, which demonstrate that the asymptotic approximations are good, even for moderate N.
引用
收藏
页码:1875 / 1951
页数:77
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