Safe Opioid Use Management of Opioid-Related Adverse Effects and Aberrant Behaviors

被引：24

作者：

Arthur, Joseph ^{[1
]}

Hui, David ^{[1
,2
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Palliat Care Rehabil & Integrat Med, Unit 1414,1515 Holcombe Blvd, Houston, TX 77030 USA

[2] Univ Texas MD Anderson Canc Ctr, Dept Gen Oncol, 1515 Holcombe Blvd, Houston, TX 77030 USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2018年 / 32卷 / 03期

基金：

美国国家卫生研究院;

关键词：

Opioid; Cancer; Aberrant behavior; Adverse effects; Nausea; Constipation; Tolerance; Sedation; CHRONIC NONCANCER PAIN; DRUG-RELATED BEHAVIOR; SUBSTANCE-ABUSE; CANCER-PATIENTS; INDUCED CONSTIPATION; INDUCED PRURITUS; ORAL MORPHINE; RISK TOOL; PART; THERAPY;

D O I：

10.1016/j.hoc.2018.01.003

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Opioids are highly effective for cancer pain but are associated with multiple adverse effects and risk of addiction. This article provides a synopsis on the management of various opioid-related adverse effects and strategies to minimize aberrant opioid use in patients who have cancer. Many adverse effects can be effectively managed. Some patients on chronic opioid therapy may demonstrate aberrant behaviors suggestive of opioid misuse or diversion. Through intensive education, longitudinal monitoring, early identification, and timely management, clinicians can optimize the risk to benefit ratio to support safe opioid use.

引用

页码：387 / +

页数：18

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