SPONDYLOARTHROPATHIES Apremilast: welcome advance in treatment of psoriatic arthritis

被引:5
作者
FitzGerald, Oliver [1 ]
机构
[1] St Vincents Univ Hosp, Rheumatol Grp, Dublin 4, Ireland
关键词
ORAL PHOSPHODIESTERASE-4 INHIBITOR; CONTROLLED-TRIAL; PHASE-3;
D O I
10.1038/nrrheum.2014.77
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The FDA has given approval for the use of apremilast in adults with active psoriatic arthritis—welcome news for patients and the rheumatology community. This commentary reviews some of the evidence for the use of apremilast and suggests some direction for future research.
引用
收藏
页码:385 / 386
页数:2
相关论文
共 8 条
  • [1] [Anonymous], 2014, OT APR FULL PRESCR I
  • [2] Comparison of effectiveness and safety of infliximab, etanercept, and adalimumab in psoriatic arthritis patients who experienced an inadequate response to previous disease-modifying antirheumatic drugs
    Atteno, Mariangela
    Peluso, Rosario
    Costa, Luisa
    Padula, Stefania
    Iervolino, Salvatore
    Caso, Francesco
    Sanduzzi, Alessandro
    Lubrano, Ennio
    Del Puente, Antonio
    Scarpa, Raffaele
    [J]. CLINICAL RHEUMATOLOGY, 2010, 29 (04) : 399 - 403
  • [3] Cutolo M, 2013, ARTHRITIS RHEUM-US, V65, pS346
  • [4] Edwards CJ, 2013, ARTHRITIS RHEUM-US, V65, pS132
  • [5] Kavanaugh A., Ann Rheum Dis
  • [6] PDE4 inhibitors: a review of current developments (2005-2009)
    Pages, Lluis
    Gavalda, Amadeu
    Lehner, Martin D.
    [J]. EXPERT OPINION ON THERAPEUTIC PATENTS, 2009, 19 (11) : 1501 - 1519
  • [7] Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis
    Schafer, P. H.
    Parton, A.
    Gandhi, A. K.
    Capone, L.
    Adams, M.
    Wu, L.
    Bartlett, J. B.
    Loveland, M. A.
    Gilhar, A.
    Cheung, Y-F
    Baillie, G. S.
    Houslay, M. D.
    Man, H-W
    Muller, G. W.
    Stirling, D. I.
    [J]. BRITISH JOURNAL OF PHARMACOLOGY, 2010, 159 (04) : 842 - 855
  • [8] Oral apremilast in the treatment of active psoriatic arthritis: Results of a multicenter, randomized, double-blind, placebo-controlled study
    Schett, Georg
    Wollenhaupt, Jurgen
    Papp, Kim
    Joos, Rik
    Rodrigues, Jude F.
    Vessey, Adele R.
    Hu, ChiaChi
    Stevens, Randall
    de Vlam, Kurt L.
    [J]. ARTHRITIS AND RHEUMATISM, 2012, 64 (10): : 3156 - 3167