Does hyperandrogenic statute in the polycystic ovary syndrome constitute an obstacle to the success of in vitro fertilization?

被引:5
|
作者
Gaddas, M. [1 ]
Chaouache, N. [1 ]
Ajina, M. [2 ]
Tabka, Z. [1 ]
Ajina, M. Zaouali [1 ]
机构
[1] Fac Med Ibn el Jazzar, Lab Physiol & Explorat Fonct, Ave Mohamed Karoui, Sousse 4000, Tunisia
[2] CHU Farhat Hached, Unite Med Reprod, Ave Ibn el Jazzar, Sousse 4000, Tunisia
来源
JOURNAL DE GYNECOLOGIE OBSTETRIQUE ET BIOLOGIE DE LA REPRODUCTION | 2016年 / 45卷 / 09期
关键词
Hyperandrogenism; IVF; Polycystic ovarian; syndrome; SYNDROME PCOS; ANDROGEN RECEPTORS; INSULIN-RESISTANCE; DOWN-REGULATION; WOMEN; TESTOSTERONE; CYCLES; CELL; STIMULATION; APOPTOSIS;
D O I
10.1016/j.jgyn.2016.08.007
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objectives. The aim of this study was to evaluate the impact of initial androgenic statute of women with polycystic ovary syndrome (SOPK) on the expected results of in vitro fertilization (FIV). Materials and methods. It is about an exploratory study carried out in 61 unfertile SOPK patients, having profited all from a cycle of FIV/ICSI (intracytoplasmic sperm injection). We have divided our population in two groups according to their hormonal androgenic statute: groups with hyperandrogenism and without hyperandrogenism. We proceeded to note the anthropometric and hormonal parameters as well as results of FIV for each of the two groups. Results. SOPK patients with hyperandrogenism are more obese than their counterparts. Also, they have more oocytes collected after ovarian induction. In addition, we did not reveal any significant differences between our two study groups concerning parameters defining FIV response. Conclusion. Our findings suggest that hyperandrogenism statute in SOPK infertile women does not seem to compromise the results of FIV. On the contrary, it would make it possible to optimize the chances to puncture more significant number of oocytes. (C) 2016 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:1091 / 1098
页数:8
相关论文
共 50 条
  • [1] Impact of Polycystic Ovary Syndrome Hyperandrogenic Phenotypes A and Non-Hyperandrogenic D on Pregnancy Outcomes After in vitro Fertilization (IVF)/Intracytoplasmic Sperm Injection (ICSI)
    Khamaiseh, Khaldoun
    Bdeir, Roba
    Abukbeer, Mohammad Mahmoud
    Khamaiseh, Rami
    Nassar, Ali
    Jnr, Dina Nasser Al-Sawadha
    Mraikhat, Rasha Rakan Al
    Khraisat, Marah Jamal
    Alawneh, Rana Radi
    Al-Mansour, Omar
    INTERNATIONAL JOURNAL OF WOMENS HEALTH, 2025, 17 : 561 - 569
  • [2] Hyperandrogenic origins of polycystic ovary syndrome - implications for pathophysiology and therapy
    Abbott, David H.
    Dumesic, Daniel A.
    Levine, Jon E.
    EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM, 2019, 14 (02) : 131 - 143
  • [3] In Vitro Fertilization for Polycystic Ovarian Syndrome
    Zolton, Jessica R.
    Torrealday, Saioa
    CLINICAL OBSTETRICS AND GYNECOLOGY, 2021, 64 (01) : 39 - 47
  • [4] Is in vitro fertilization the answer in polycystic ovary syndrome?
    Gupta, Sajal
    Sinha, Annika
    FERTILITY AND STERILITY, 2021, 115 (02) : 330 - 331
  • [5] A woman with polycystic ovary syndrome treated for infertility by in vitro fertilization
    Tang, Thomas
    Balen, Adam H.
    NATURE REVIEWS ENDOCRINOLOGY, 2009, 5 (08) : 462 - 465
  • [6] The effect of serum and follicular fluid amyloid-associated protein levels on in vitro fertilization outcome in patients with polycystic ovary syndrome
    Timur, Hakan
    Yimaz, Nafiye
    Kahyaoglu, Inci
    Inal, Hasan Ali
    Erkaya, Salim
    JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 2015, 32 (11) : 1637 - 1642
  • [7] Does metformin affect the ovarian response to gonadotropins for in vitro fertilization treatment in patients with polycystic ovary syndrome and reduced ovarian reserve? A randomized controlled trial
    Palomba, Stefano
    Falbo, Angela
    Di Cello, Annalisa
    Cappiello, Fulvio
    Tolino, Achille
    Zullo, Fulvio
    FERTILITY AND STERILITY, 2011, 96 (05) : 1128 - 1133
  • [8] A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
    Xue, Ping
    Wang, Zhiqiang
    Fu, Xiaomin
    Vvang, Junjiang
    Punchhi, Gopika
    Wolfe, Andrew
    Wu, Sheng
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2018, (140):
  • [9] Effect of finasteride on ovulation induction in nonresponder (hyperandrogenic) polycystic ovary syndrome (PCOS) women
    Tartagni, Massimo
    Cicinelli, Ettore
    De Pergola, Giovanni
    Lavopa, Cristina
    Di Naro, Edoardo
    De Salvia, Maria Antonietta
    Loverro, Giuseppe
    FERTILITY AND STERILITY, 2010, 94 (01) : 247 - 249
  • [10] Comparison of in vitro fertilisation success in patients with polycystic ovary syndrome and tubal factor
    Nejad, Ensieh Shahrokh Tehrani
    Saedi, Tahereh
    Saedi, Sedigheh
    Rashidi, Batool Hossein
    Nekoo, Zahra Azimi
    Jahangiri, Nadia
    GYNECOLOGICAL ENDOCRINOLOGY, 2011, 27 (02) : 117 - 120