Cyclosporins from Mycelium sterilae MS 2929

被引:4
作者
Kuzma, Marek [1 ]
Sedmera, Petr [1 ]
Jegorov, Alexandr [2 ]
Havlicek, Vladimir [1 ]
机构
[1] Acad Sci Czech Republ, Inst Microbiol, CR-14220 Prague, Czech Republic
[2] IVAX Pharmaceut, TAPI Galena, Res & Dev, Ceske Budejovice 37005, Czech Republic
来源
JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 01期
关键词
IN-VITRO BIOSYNTHESIS; FAST-ATOM-BOMBARDMENT; A DERIVATIVES; SYNTHETASE; MECHANISMS; PEPTOLIDE; SHIFT;
D O I
10.1021/np8003968
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The structures of two new cyclosporins were elucidated by NMR and MS methods as cyclo[-MeBmt(1)-Abu(2)-Sar(3)-MeLeu(4)-Val(5)-MeLeu(6)-Ala(7)-D-Ala(8)-MeLeu(9)-MeNva(10)-MeVal(11)-] and cyclo[-MeBmt(1)-Abu(2)-Sar(3)-MeLeu(4)-Abu(5)-MeLeu(6)-Ala(7)-D-Ala(8)-MeLeu(9)-MeLeu(10)-MeVal(11)-].
引用
收藏
页码:159 / 163
页数:5
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