Waist circumference and the risk of lumbar and femur fractures: a nationwide population-based cohort study

被引:14
作者
Park, G. R. [1 ]
Kim, H. S. [1 ]
Kim, Y. T. [1 ]
Chung, H. J. [1 ]
Ha, S. J. [2 ]
Kim, D. W. [2 ]
Kang, D. R. [3 ]
Kim, J. Y. [1 ]
Lee, M. Y. [1 ]
Lee, J. Y. [1 ,4 ]
机构
[1] Yonsei Wonju Coll Med, Dept Internal Med, Wonju, South Korea
[2] Natl Hlth Insurance Serv, Big Data Dept, Wonju, South Korea
[3] Yonsei Wonju Coll Med, Dept Precis Med, Wonju, South Korea
[4] Yonsei Univ, Inst Convergence Sci, Ctr Evidence Based Med, Wonju, South Korea
关键词
Waist circumference; Lumbar fracture; Femur fracture; BMI; Sex; BODY-MASS INDEX; BONE-MINERAL DENSITY; HIP FRACTURE; FAT MASS; VERTEBRAL FRACTURES; ABDOMINAL OBESITY; WOMEN; OSTEOPOROSIS; HEALTH; BURDEN;
D O I
10.26355/eurrev_202102_24822
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Although obesity is known to have an influence on fracture, the relationship between lumbar and femur fractures and weight or waist circumference is controversial. We investigated the incidence of fracture with regards to waist circumference using the customised database of the Korean National Health Insurance Service (NHIS). Among 8,922,940 adults who participated at least twice in the NHIS National Health Check-up Program in South Korea between 2009 and 2011, 1,556,751 subjects (780,074 men and 776,677 women) were extracted. Over a mean follow-up of 6.5 years, multivariate-adjusted logistic regression analysis demonstrated that higher waist circumference was associated with an increased risk of femur fractures in both males and females. Moreover, the incidence of lumbar fractures was also positively associated with an increased waist circumference in males and females. An increased waist circumference showed a positive linear relationship with the risk of lumbar and femur fractures in both males and females.
引用
收藏
页码:1198 / 1205
页数:8
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