The search for a predictor of CD4 cell count continues: Total lymphocyte count is not a substitute for CD4 cell count in the management of HIV-Infected individuals in a resource-limited setting

被引：27
|
作者：
Akinola, NO [1 ]
Olasode, O
Adediran, IA
Onayemi, O
Murainah, A
Irinoye, O
Elujoba, AA
Durosinmi, MA
机构：
[1] Obafemi Awolowo Univ, Fac Basic Med Sci, Dept Haematol & Immunol, Ife, Nigeria
[2] Obafemi Awolowo Univ, Dept Dermatol & Venereol, Ife, Nigeria
[3] Obafemi Awolowo Univ, Dept Nursing Sci, Ife, Nigeria
[4] Obafemi Awolowo Univ, Dept Pharmacognosy, Ife, Nigeria
来源：
CLINICAL INFECTIOUS DISEASES | 2004年 / 39卷 / 04期
关键词：
D O I：
10.1086/422722
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Total lymphocyte count (TLC) has been recommended as a substitute for CD4 cell count for the management of HIV-infected individuals living in resource-limited settings. To confirm this, 151 TLCs and CD4 cell counts were obtained from 109 patients who had not yet started treatment and analyzed. CD4 cell counts of <200 cells/mm(3) were found in 42 cases (37.8%) with TLCs of ≥1200 cells/mm(3). Thus, 1 in 3 individuals would have been deprived of needed treatment. Therefore, in this setting, TLC is not a reliable predictor of CD4 cell count in HIV-infected individuals.
引用
收藏
页码：579 / 581
页数：3
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