The search for a predictor of CD4 cell count continues: Total lymphocyte count is not a substitute for CD4 cell count in the management of HIV-Infected individuals in a resource-limited setting

被引：27

作者：

Akinola, NO ^{[1
]}

Olasode, O

Adediran, IA

Onayemi, O

Murainah, A

Irinoye, O

Elujoba, AA

Durosinmi, MA

机构：

[1] Obafemi Awolowo Univ, Fac Basic Med Sci, Dept Haematol & Immunol, Ife, Nigeria

[2] Obafemi Awolowo Univ, Dept Dermatol & Venereol, Ife, Nigeria

[3] Obafemi Awolowo Univ, Dept Nursing Sci, Ife, Nigeria

[4] Obafemi Awolowo Univ, Dept Pharmacognosy, Ife, Nigeria

来源：

CLINICAL INFECTIOUS DISEASES | 2004年 / 39卷 / 04期

关键词：

D O I：

10.1086/422722

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Total lymphocyte count (TLC) has been recommended as a substitute for CD4 cell count for the management of HIV-infected individuals living in resource-limited settings. To confirm this, 151 TLCs and CD4 cell counts were obtained from 109 patients who had not yet started treatment and analyzed. CD4 cell counts of <200 cells/mm(3) were found in 42 cases (37.8%) with TLCs of ≥1200 cells/mm(3). Thus, 1 in 3 individuals would have been deprived of needed treatment. Therefore, in this setting, TLC is not a reliable predictor of CD4 cell count in HIV-infected individuals.

引用

页码：579 / 581

页数：3

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