Recent developments in chemical reactivity of N,N-dimethylenamino ketones as synthons for various heterocycles

被引：80

作者：

Gaber, Hatem M. ^{[1
]}

Bagley, Mark C. ^{[2
]}

Muhammad, Zeinab A. ^{[1
]}

Gomha, Sobhi M. ^{[3
]}

机构：

[1] Natl Org Drug Control & Res NODCAR, POB 29, Cairo, Egypt

[2] Univ Sussex, Dept Chem, Sch Life Sci, Brighton BN1 9QJ, E Sussex, England

[3] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt

来源：

RSC ADVANCES | 2017年 / 7卷 / 24期

基金：

英国工程与自然科学研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

ONE-POT SYNTHESIS; FUNCTIONALLY-SUBSTITUTED HETEROAROMATICS; MICROWAVE-ASSISTED SYNTHESIS; BUILDING-BLOCKS; ORGANIC-SYNTHESIS; REGIOSELECTIVE SYNTHESIS; 3-COMPONENT REACTIONS; CASCADE SYNTHESIS; EFFICIENT ROUTE; PART;

D O I：

10.1039/c7ra00683g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The current review presents recent progress in the utility of N,N-dimethyl enaminones as building blocks for a diverse range of acyclic, carbocyclic, five-and six-membered heterocyclic a broad range of heterocyclic and fused heterocyclic derivatives. Most importantly, these N, N-dimethyl analogues have proven to be of biological interest and provide an access to new class of biologically active heterocyclic compounds for biomedical applications. All of these topics are drawn from the recent literature till 2016.

引用

页码：14562 / 14610

页数：49

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