Is Dietetic Treatment for Undernutrition in Older Individuals in Primary Care Cost-Effective?

被引:13
作者
Schilp, Janneke [1 ,2 ,3 ]
Bosmans, Judith E. [1 ,2 ,4 ]
Kruizenga, Hinke M. [1 ,2 ,3 ,5 ,6 ,7 ]
Wijnhoven, Hanneke A. H. [1 ,2 ]
Visser, Marjolein [1 ,2 ,8 ]
机构
[1] Vrije Univ Amsterdam, Fac Earth & Life Sci, Dept Hlth Sci, NL-1081 HV Amsterdam, Netherlands
[2] Vrije Univ Amsterdam, Fac Earth & Life Sci, EMGO Inst Hlth & Res, NL-1081 HV Amsterdam, Netherlands
[3] Dutch Malnutr Steering Grp, Amsterdam, Netherlands
[4] Vrije Univ Amsterdam, Fac Earth & Life Sci, Dept Hlth Sci, Dept Hlth Econ & Hlth Technol Assessment, NL-1081 HV Amsterdam, Netherlands
[5] Vrije Univ Amsterdam, Med Ctr, Dept Nutr & Dietet, Amsterdam, Netherlands
[6] Vrije Univ Amsterdam, Med Ctr, Dept Internal Med, Amsterdam, Netherlands
[7] Vrije Univ Amsterdam, Med Ctr, EMGO Inst Hlth & Care Res, Amsterdam, Netherlands
[8] Vrije Univ Amsterdam, Med Ctr, Dept Epidemiol & Biostat, Amsterdam, Netherlands
关键词
Undernutrition; cost-effectiveness; dietetic treatment; primary care; QUALITY-OF-LIFE; NUTRITIONAL ASSESSMENT; CONTROLLED-TRIAL; CLINICAL-TRIALS; COMMUNITY; SUPPLEMENTATION; RISK; HOSPITALIZATION; PROTEIN; WOMEN;
D O I
10.1016/j.jamda.2013.10.010
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Objectives: Undernutrition in older age is associated with adverse clinical outcomes and high health care costs. This study aimed to evaluate the cost-effectiveness of a dietetic treatment in primary care compared with usual care in older, undernourished, community-dwelling individuals. Design: A parallel randomized controlled trial. Setting: Primary care. Participants: A total of 146 undernourished, independently living older (>= 65 years) individuals. Intervention: Dietetic treatment. Measurements: Main outcomes were change in kilogram body weight compared with baseline and quality-adjusted life years (QALYs) after 6 months. Costs were measured from a societal perspective. The main analysis was performed according to the intention-to-treat principle. Multiple imputation was used to impute missing data and bootstrapping was used to estimate uncertainty surrounding cost differences and incremental cost-effectiveness ratios. Cost-effectiveness planes and cost-effectiveness acceptability curves were estimated. Results: The participants were randomized to receive either dietetic treatment (n = 72) or usual care (n = 74). After 6 months, no statistically significant differences were found between the dietetic treatment and usual care group in body weight change (mean difference 0.78 kg, 95% CI -0.26-1.82), QALYs (mean difference 0.001, 95% CI -0.04-0.04) and total costs (mean difference (sic)1645, 95% CI -525-3547). The incremental cost-utility ratio (ICUR) for QALYs was not interpretable. The incremental cost-effectiveness ratio (ICER) for body weight gain was 2111. The probability that dietetic treatment is cost-effective compared with usual care was 0.78 for a ceiling ratio of (sic)5000 for body weight and 0.06 for a ceiling ratio of (sic)20.000 for QALY. Conclusion: In this study, dietetic treatment in older, undernourished, community-dwelling individuals was not cost-effective compared with usual care. (C) 2014 - American Medical Directors Association, Inc. All rights reserved.
引用
收藏
页码:226.e7 / 226.e13
页数:7
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