Effects of waterborne fluoxetine on stress response and osmoregulation in zebrafish

被引：32

作者：

Abreu, Murilo S. ^{[1
]}

Giacomini, Ana Cristina V. ^{[1
,2
]}

Koakoski, Gessi ^{[1
]}

Oliveira, Thiago A. ^{[1
]}

Gusso, Darlan ^{[2
]}

Baldisserotto, Bernardo ^{[1
]}

Barcellos, Leonardo J. G. ^{[1
,2
]}

机构：

[1] Univ Fed Santa Maria, Programa Posgrad Farmacol, BR-97119900 Santa Maria, RS, Brazil

[2] Univ Passo Fundo, Programa Posgrad Bioexpt, Passo Fundo, RS, Brazil

来源：

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY | 2015年 / 40卷 / 03期

关键词：

Danio rerio; Osmoregulation; Cortisol; Homeostasis; Psychotropic drug; SSRI; CORTISOL; PHARMACEUTICALS; GROWTH;

D O I：

10.1016/j.etap.2015.09.001

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The presence of fluoxetine in aquatic environments has been reported for decades. Here, we investigate the effects of exposure to fluoxetine on the stress response and osmoregulation in zebrafish. We show that stress response alters osmoregulation and that fluoxetine inhibits these stress-related changes in osmoregulation. The results suggest that the presence of fluoxetine in aquatic ecosystems can cause changes in response to stress and osmoregulation in fish. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：704 / 707

页数：4

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