Bio-Inspired Photonic-Crystal Microchip for Fluorescent Ultratrace Detection

被引：261

作者：

Hou, Jue ^{[1
,2
]}

Zhang, Huacheng ^{[1
,2
]}

Yang, Qiang ^{[1
,2
]}

Li, Mingzhu ^{[1
]}

Song, Yanlin ^{[1
]}

Jiang, Lei ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, BNLMS, Key Lab Organ Solids,Key Lab Green Printing, Beijing 100080, Peoples R China

[2] Univ Chinese Acad Sci, Beijing, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2014年 / 53卷 / 23期

关键词：

cocaine; enrichment; fluorescence enhancement; photonic crystals; ultratrace detection; LABEL-FREE DETECTION; MAGNETIC NANOPARTICLES; PROTEIN-DETECTION; FORENSIC-SCIENCE; COCAINE; SENSOR; AMPLIFICATION; WETTABILITY; EXPLOSIVES; CHEMISTRY;

D O I：

10.1002/anie.201400686

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ultratrace detection attracts great interest because it is still a challenge to the early diagnosis and drug testing. Enriching the targets from highly diluted solutions to the sensitive area is a promising method. Inspired by the fog-collecting structure on Stenocara beetle's back, a photonic-crystal (PC) microchip with hydrophilic-hydrophobic micropattern was fabricated by inkjet printing. This device was used to realize high-sensitive ultratrace detection of fluorescence analytes and fluorophore-based assays. Coupled with the fluorescence enhancement effect of a PC, detection down to 10(-16) mol L-1 was achieved. This design can be combined with biophotonic devices for the detection of drugs, diseases, and pollutions of the ecosystem.

引用

页码：5791 / 5795

页数：5

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