Cytotoxic constituents of roots of Chaerophyllum hirsutum

被引：34
作者：
Dall'Acqua, S
Viola, G
Piacente, S
Cappelletti, EM
Innocenti, G
机构：
[1] Univ Padua, Dipartimento Sci Farmaceut, I-35131 Padua, Italy
[2] Univ Salerno, Dipartimento Sci Farmaceut, I-84084 Salerno, Italy
[3] Univ Padua, Dipartimento Biol, I-35121 Padua, Italy
来源：
JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 09期
关键词：
D O I：
10.1021/np040046w
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new lignan derivatives (1 and 2), along with the known scopoletin (3), methyl caffeate (4), falcarindiol (5), 3,5-dicaffeoylquinic acid, 3,5-dicaffeoylquinic methyl ester, chlorogenic acid, p-hydroxyphenylethyl-trans-ferulate, and vanillin, were isolated from extracts of the roots of Chaerophyllum hirsutum. Structure elucidation of the new compounds was carried out by 1D and 2D NMR experiments and by HRMS analysis. Several of the isolated compounds were tested for their cytotoxic activity against the HL-60, HT-1080, LoVo, and LoVo/Doxo cell lines.
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页码：1588 / 1590
页数：3
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