Assessing anaphylactic risk? Consider mast cell clonality

被引:45
作者
Metcalfe, Dean D. [1 ]
Schwartz, Lawrence B. [2 ]
机构
[1] NIAID, Lab Allerg Dis, NIH, Bethesda, MD 20892 USA
[2] Virginia Commonwealth Univ, Dept Internal Med, Richmond, VA USA
关键词
Anaphylaxis; tryptase; mast cells; KIT; venom; SYSTEMIC MASTOCYTOSIS; HUMAN TRYPTASE; KIT; BLOOD;
D O I
10.1016/j.jaci.2009.02.003
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:687 / 688
页数:2
相关论文
共 20 条
[1]   Demonstration of an aberrant mast-cell population with clonal markers in a subset of patients with "idiopathic" anaphylaxis [J].
Akin, Cem ;
Scott, Linda M. ;
Kocabas, Can N. ;
Kushnir-Sukhov, Nataliya ;
Brittain, Erica ;
Noel, Pierre ;
Metcalfe, Dean D. .
BLOOD, 2007, 110 (07) :2331-2333
[2]   Clonal mast cell disorders in patients with systemic reactions to Hymenoptera stings and increased serum tryptase levels [J].
Bonadonna, Patrizia ;
Perbellini, Omar ;
Passalacqua, Giovanni ;
Caruso, Beatrice ;
Colarossi, Sabrina ;
Dal Fior, Daniela ;
Castellani, Luca ;
Bonetto, Chiara ;
Frattini, Francesco ;
Dama, Annarita ;
Martinelli, Giovanni ;
Chilosi, Marco ;
Senna, Gianenrico ;
Pizzolo, Giovanni ;
Zanotti, Roberta .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2009, 123 (03) :680-686
[3]   Anaphylaxis in patients with mastocytosis: a study on history, clinical features and risk factors in 120 patients [J].
Brockow, K. ;
Jofer, C. ;
Behrendt, H. ;
Ring, J. .
ALLERGY, 2008, 63 (02) :226-232
[4]   Omalizumab for the treatment of unprovoked anaphylaxis in patients with systemic mastocytosis [J].
Carter, Melody C. ;
Robyn, Jamie A. ;
Bressler, Peter B. ;
Walker, John C. ;
Shapiro, Gail G. ;
Metcalfe, Dean D. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 119 (06) :1550-1551
[5]   Safety and effectiveness of immunotherapy in patients with indolent systemic mastocytosis presenting with Hymenoptera venom anaphylaxis [J].
De Olano, David Gonzalez ;
Alvarez-Twose, Ivan ;
Esteban-Lopez, Maria I. ;
Sanchez-Munoz, Laura ;
Durana, Maria D. Alonso Diaz ;
Vega, Arantza ;
Garcia-Montero, Andres ;
Gonzalez-Mancebo, Eloina ;
Belver, Teresa ;
Herrero-Gil, Maria D. ;
Fernandez-Rivas, Montserrat ;
Orfao, Alberto ;
de la Hoz, Belen ;
Castells, Mariana C. ;
Escribano, Luis .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2008, 121 (02) :519-526
[6]  
Horny H-P., 2008, WHO classification of Tumours of Haematopoietic and Lymphoid Tissues, V4th, P54
[7]   Kit- and FcεRI-induced differential phosphorylation of the transmembrane adaptor molecule NTAL/LAB/LAT2 allows flexibility in its scaffolding function in mast cells [J].
Iwaki, Shoko ;
Spicka, Jiri ;
Tkaczyk, Christine ;
Jensen, Bettina M. ;
Fururnoto, Yasuko ;
Charles, Nicolas ;
Kovarova, Martina ;
Rivera, Juan ;
Horejsi, Vaclav ;
Metcalfe, Dean D. ;
Gilfillan, Alasdair M. .
CELLULAR SIGNALLING, 2008, 20 (01) :195-205
[8]   Concurrent inhibition of kit- and FcεRI-mediated signaling:: Coordinated suppression of mast cell activation [J].
Jensen, Bettina M. ;
Beaven, Michael A. ;
Iwaki, Shoko ;
Metcalfe, Dean D. ;
Gilfillan, Alasdair M. .
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2008, 324 (01) :128-138
[9]   Constitutively raised serum concentrations of mast-cell tryptase and severe anaphylactic reactions to Hymenoptera stings [J].
Ludolph-Hauser, D ;
Ruëff, F ;
Fries, C ;
Schöpf, P ;
Przybilla, B .
LANCET, 2001, 357 (9253) :361-362
[10]   The Problem of Anaphylaxis and Mastocytosis [J].
Mueller, Ulrich R. ;
Haeberli, Gabrielle .
CURRENT ALLERGY AND ASTHMA REPORTS, 2009, 9 (01) :64-70