PredictRegulon: a web server for the prediction of the regulatory protein binding sites and operons in prokaryote genomes

被引：37

作者：

Yellaboina, S

Seshadri, J

Kumar, MS

Ranjan, A ^{[1
]}

机构：

[1] EMBnet India Node, Ctr DNA Fingerprinting & Diagnost, Computat & Funct Gen Grp, Hyderabad 500076, Andhra Pradesh, India

[2] EMBnet India Node, Ctr DNA Fingerprinting & Diagnost, Mol Oncol Lab, Hyderabad 500076, Andhra Pradesh, India

来源：

NUCLEIC ACIDS RESEARCH | 2004年 / 32卷

关键词：

D O I：

10.1093/nar/gkh364

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An interactive web server is developed for predicting the potential binding sites and its target operons for a given regulatory protein in prokaryotic genomes. The program allows users to submit known or experimentally determined binding sites of a regulatory protein as ungapped multiple sequence alignments. It analyses the upstream regions of all genes in a user-selected prokaryote genome and returns the potential binding sites along with the downstream co-regulated genes (operons). The known binding sites of a regulatory protein can also be used to identify its orthologue binding sites in phylogeneticaly related genomes where the trans-acting regulator protein and cognate cis-acting DNA sequences could be conserved. PredictRegulon can be freely accessed from a link on our world wide web server: http://www.cdfd.org.in/predictregulon/.

引用

页码：W318 / W320

页数：3

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