Quality evaluation of Lycium barbarum L. fruits from different regions in China based on 2-O-β-D-glucopyranosyl-L-ascorbic acid

被引：4
作者：
Zhu, Baojie [1 ]
Zhang, Wanxin [1 ]
Qin, You [1 ]
Zhao, Jing [1 ]
Li, Shaoping [1 ]
机构：
[1] Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau, Peoples R China
来源：
JOURNAL OF FOOD COMPOSITION AND ANALYSIS | 2022年 / 109卷
基金：
国家重点研发计划;
关键词：
2-O-beta-D-glucopyranosyl-L-ascorbic acid (AA2 beta G); Hydrophilic interaction liquid chromatography; Lycium barbarum L. fruits; Response surface methodology; ASCORBIC-ACID; 2-O-(BETA-D-GLUCOPYRANOSYL)ASCORBIC ACID; CONSTITUENTS; ANTIOXIDANT; ANALOG;
D O I：
10.1016/j.jfca.2022.104512
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The selection of a quality marker is crucial for quality control of Lycium barbarum L. fruits, which are widely used in the food and drug industries, especially as herbal medicine, and functional food. However, using betaine, the quality marker in the current standard, for discrimination of L. barbarum fruits lacks specificity. In this study, a vitamin C derivative, 2-O-beta-D-glucopyranosyl-L-ascorbic acid (AA-2 beta G), was first used as an antioxidant biomarker instead of betaine for the quality control of L. barbarum fruits from different regions. Three-factor three-level response surface methodology was used to optimize extraction conditions, which indicated that the optimal conditions of AA-2 beta G were 75% ethanol as extraction solvent, 1:25 of solvent-to-solid ratio, and 30 min for extraction time. Hydrophilic interaction liquid chromatography method was applied for the quantification of AA-2 beta G. The results showed that the content of AA-2 beta G in L. barbarum fruits from different regions was above 9 mg/g except for samples of NLB 8, NLB 30 and NLB 74. All samples were classified into three clusters with Hierarchical Cluster Analysis, and most of them belong to cluster III with the content of AA-2 beta G in the range of 9.04-11.8 mg/g.
引用
收藏
页数：6
相关论文
共 26 条
[1]   A review of botanical characteristics, phytochemistry, clinical relevance in efficacy and safety of Lycium barbarum fruit (Goji) [J].
Amagase, Harunobu ;
Farnsworth, Norman R. .
FOOD RESEARCH INTERNATIONAL, 2011, 44 (07) :1702-1717
[2]   Ascorbic Acid Derivative 2-O-β-D-Glucopyranosyl-L-Ascorbic Acid from the Fruit of Lycium barbarum Modulates Microbiota in the Small Intestine and Colon and Exerts an Immunomodulatory Effect on Cyclophosphamide-Treated BALB/c Mice [J].
Huang, Kaiyin ;
Yan, Yamei ;
Chen, Dan ;
Zhao, Ya ;
Dong, Wei ;
Zeng, Xiaoxiong ;
Cao, Youlong .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, 68 (40) :11128-11143
[3]   2-O-β-D-Glucopyranosyl-L-ascorbic Acid, an Ascorbic Acid Derivative Isolated from the Fruits of Lycium Barbarum L., Modulates Gut Microbiota and Palliates Colitis in Dextran Sodium Sulfate-Induced Colitis in Mice [J].
Huang, Kaiyin ;
Dong, Wei ;
Liu, Wanyu ;
Yan, Yamei ;
Wan, Peng ;
Peng, Yujia ;
Xu, Yujuan ;
Zeng, Xiaoxiong ;
Cao, Youlong .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 67 (41) :11408-11419
[4]   Response surface methodology [J].
Khuri, Andre I. ;
Mukhopadhyay, Siuli .
WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL STATISTICS, 2010, 2 (02) :128-149
[5]  
Kocyigit E., 2017, Int J Chin Med, V1, P1
[6]   Comparison and Characterization of Compounds with Antioxidant Activity in Lycium barbarum Using High-Performance Thin Layer Chromatography Coupled with DPPH Bioautography and Tandem Mass Spectrometry [J].
Lam, Shing-Chung ;
Luo, Zhen ;
Wu, Ding-Tao ;
Cheong, Kit-Leong ;
Hu, De-Jun ;
Xia, Zu-Meng ;
Zhao, Jing ;
Li, Shao-Ping .
JOURNAL OF FOOD SCIENCE, 2016, 81 (06) :C1378-C1384
[7]   Synthesis and α-Glycosidase Inhibitory Activity of Three Ascorbic Acid Glycosides [J].
Ma, Jimei ;
Xie, Lingyun ;
Wang, Longwen ;
Chen, Hangwei ;
Zeng, Zhen ;
Chen, Hao ;
Jiang, Hong .
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 37 (06) :1426-1432
[8]   Polyphenols from Lycium barbarum (Goji) Fruit European Cultivars at Different Maturation Steps: Extraction, HPLC-DAD Analyses, and Biological Evaluation [J].
Mocan, Andrei ;
Cairone, Francesco ;
Locatelli, Marcello ;
Cacciagrano, Francesco ;
Carradori, Simone ;
Vodnar, Dan C. ;
Crisan, Gianina ;
Simonetti, Giovanna ;
Cesa, Stefania .
ANTIOXIDANTS, 2019, 8 (11)
[9]   UHPLC-QTOF-MS analysis of bioactive constituents from two Romanian Goji (Lycium barbarum L.) berries cultivars and their antioxidant, enzyme inhibitory, and real-time cytotoxicological evaluation [J].
Mocan, Andrei ;
Moldovan, Cadmiel ;
Zengin, Gokhan ;
Bender, Onur ;
Locatelli, Marcello ;
Simirgiotis, Mario ;
Atalay, Arzu ;
Vodnar, Dan Cristian ;
Rohn, Sascha ;
Crisan, Gianina .
FOOD AND CHEMICAL TOXICOLOGY, 2018, 115 :414-424
[10]  
Pharmacopoeia commission of people's republic of China, 2020, PHARMACOPOEIA PEOPLE
123