Bioinformatics tools used for whole-genome sequencing analysis of Neisseria gonorrhoeae: a literature review

被引:5
作者
Singh, Reema [1 ]
Kusalik, Anthony [2 ,3 ]
Dillon, Jo-Anne R. [1 ,4 ]
机构
[1] Univ Saskatchewan, Coll Med, Dept Biochem Microbiol & Immunol, Saskatoon, SK, Canada
[2] Univ Saskatchewan, Dept Comp Sci, Saskatoon, SK, Canada
[3] Univ Saskatchewan, Bioinformat Program, Saskatoon, SK, Canada
[4] Vaccine & Infect Dis Org, Saskatoon, SK, Canada
基金
加拿大健康研究院;
关键词
bioinformatics; Neisseria gonorrhoeae; whole genome sequencing; antimicrobial resistance; molecular epidemiology; strain typing; population structure; EXTENDED-SPECTRUM CEPHALOSPORINS; MOLECULAR RESISTANCE MECHANISMS; ANTIMICROBIAL RESISTANCE; ANTIBIOTIC-RESISTANCE; DECREASED SUSCEPTIBILITY; TRANSMISSION CLUSTERS; REVEALS TRANSMISSION; PHYLOGENETIC TREES; FC428; CLONE; SINGLE-CELL;
D O I
10.1093/bfgp/elab028
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Whole-genome sequencing (WGS) data are well established for the investigation of gonococcal transmission, antimicrobial resistance prediction, population structure determination and population dynamics. A variety of bioinformatics tools, repositories, services and platforms have been applied to manage and analyze Neisseria gonorrhoeae WGS datasets. This review provides an overview of the various bioinformatics approaches and resources used in 105 published studies (as of 30 April 2021). The challenges in the analysis of N. gonorrhoeae WGS datasets, as well as future bioinformatics requirements, are also discussed.
引用
收藏
页码:78 / 89
页数:12
相关论文
共 201 条
  • [51] Gernert KM, 2020, LANCET MICROBE, V1, pE154, DOI 10.1016/S2666-5247(20)30059-8
  • [52] Modern technologies and algorithms for scaffolding assembled genomes
    Ghurye, Jay
    Pop, Mihai
    [J]. PLOS COMPUTATIONAL BIOLOGY, 2019, 15 (06)
  • [53] Use of Whole Genome Sequencing for the Molecular Comparison of Neisseria gonorrhoeae Isolates With Decreased Susceptibility to Extended Spectrum Cephalosporins From 2 Geographically Different Regions in America
    Gianecini, Ricardo A.
    Zittermann, Sandra
    Oviedo, Claudia
    Galas, Marcelo
    Pardo, Pilar Ramon
    Allen, Vanessa G.
    Galarza, Patricia
    Melano, Roberto G.
    [J]. SEXUALLY TRANSMITTED DISEASES, 2019, 46 (08) : 548 - 555
  • [54] Genome-based epidemiology and antimicrobial resistance determinants of Neisseria gonorrhoeae isolates with decreased susceptibility and resistance to extended-spectrum cephalosporins in Argentina in 2011-16
    Gianecini, Ricardo A.
    Golparian, Daniel
    Zittermann, Sandra
    Litvik, Ana
    Gonzalez, Silvia
    Oviedo, Claudia
    Melano, Roberto G.
    Unemo, Magnus
    Galarza, Patricia
    Cristaldo, P.
    Gonzalez, M.
    Cuenca, N.
    Caniggia, L.
    Montibello, S.
    Buscemi, L.
    Smayevski, J.
    Turco, M.
    Garbaz, C.
    Morales, M.
    Alfonso, C.
    Montoto, M.
    Marcato, M.
    Casimiro, A.
    Cervetto, M.
    Giovanakis, M.
    Apestey, N.
    Casanova, N.
    Di Bartolomeo, S.
    Machain, M.
    Garrone, M.
    Padlog, R.
    Vilches, V.
    Sparo, M.
    Retes, A.
    Tognieri, A.
    Almuzara, M.
    Rizzo, M.
    Cagnoni, V.
    Littvik, A.
    Gonzalez, S.
    Mendez, E.
    Morano, S.
    Valles, J.
    Nepote, A.
    Piccoli, L.
    Solis, H.
    Guillen, A.
    Amador, S.
    Guantay, C.
    Arias, C.
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2019, 74 (06) : 1551 - 1559
  • [55] Neisseria gonorrhoeae Sequence Typing for Antimicrobial Resistance (NG-STAR) clonal complexes are consistent with genomic phylogeny and provide simple nomenclature, rapid visualization and antimicrobial resistance (AMR) lineage predictions
    Golparian, Daniel
    Sanchez-Buso, Leonor
    Cole, Michelle
    Unemo, Magnus
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2021, 76 (04) : 940 - 944
  • [56] Genomic epidemiology of Neisseria gonorrhoeae elucidating the gonococcal antimicrobial resistance and lineages/sublineages across Brazil, 2015-16
    Golparian, Daniel
    Bazzo, Maria Luiza
    Golfetto, Lisleia
    Gaspar, Pamela Cristina
    Schorner, Marcos Andre
    Benzaken, Adele Schwartz
    Ramos, Mauro Cunha
    Ferreira, William Antunes
    Alonso Neto, Jose Boullosa
    Mendes Pereira, Gerson Fernando
    Unemo, Magnus
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2020, 75 (11) : 3163 - 3172
  • [57] Genomic evolution of Neisseria gonorrhoeae since the preantibiotic era (1928-2013): antimicrobial use/misuse selects for resistance and drives evolution
    Golparian, Daniel
    Harris, Simon R.
    Sanchez-Buso, Leonor
    Hoffmann, Steen
    Shafer, William M.
    Bentley, Stephen D.
    Jensen, Jorgen S.
    Unemo, Magnus
    [J]. BMC GENOMICS, 2020, 21 (01)
  • [58] Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018
    Golparian, Daniel
    Rose, Lisa
    Lynam, Almida
    Mohamed, Aia
    Bercot, Beatrice
    Ohnishi, Makoto
    Crowley, Brendan
    Unemo, Magnus
    [J]. EUROSURVEILLANCE, 2018, 23 (47): : 6 - 9
  • [59] Genomic Epidemiology of Gonococcal Resistance to Extended-Spectrum Cephalosporins, Macrolides, and Fluoroquinolones in the United States, 2000-2013
    Grad, Yonatan H.
    Harris, Simon R.
    Kirkcaldy, Robert D.
    Green, Anna G.
    Marks, Debora S.
    Bentley, Stephen D.
    Trees, David
    Lipsitch, Marc
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2016, 214 (10) : 1579 - 1587
  • [60] Genomic epidemiology of Neisseria gonorrhoeae with reduced susceptibility to cefixime in the USA: a retrospective observational study
    Grad, Yonatan H.
    Kirkcaldy, Robert D.
    Trees, David
    Dordel, Janina
    Harris, Simon R.
    Goldstein, Edward
    Weinstock, Hillard
    Parkhill, Julian
    Hanage, William P.
    Bentley, Stephen
    Lipsitch, Marc
    [J]. LANCET INFECTIOUS DISEASES, 2014, 14 (03) : 220 - 226