Selective vertical transmission of HIV: lamivudine-resistant maternal clone undetectable by conventional resistance testing

被引:10
作者
Niehues, T [1 ]
Walter, H
Homeff, G
Wahn, V
Schmidt, B
机构
[1] Univ Dusseldorf, Childrens Hosp, D-4000 Dusseldorf, Germany
[2] Univ Erlangen Nurnberg, Inst Clin & Mol Virol, Natl Reference Ctr Retroviruses, D-8520 Erlangen, Germany
[3] Univ Halle Wittenberg, Childrens Hosp, Halle, Germany
关键词
D O I
10.1097/00002030-199912030-00025
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:2482 / 2484
页数:3
相关论文
共 5 条
[1]   Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme [J].
Back, NKT ;
Nijhuis, M ;
Keulen, W ;
Boucher, CAB ;
Essink, BBO ;
vanKuilenburg, ABP ;
vanGennip, AH ;
Berkhout, B .
EMBO JOURNAL, 1996, 15 (15) :4040-4049
[2]   Selective vertical transmission of HIV-1 antiretroviral resistance mutations [J].
Colgrove, RC ;
Pitt, J ;
Chung, PH ;
Welles, SL ;
Japour, AJ .
AIDS, 1998, 12 (17) :2281-2288
[3]   Rapid disease progression in HIV-1 perinatally infected children born to mothers receiving zidovudine monotherapy during pregnancy [J].
de Martino, M ;
Galli, L ;
Tovo, PA ;
Gabiano, C ;
Zappa, M .
AIDS, 1999, 13 (08) :927-933
[4]   MOTHER-TO-CHILD TRANSMISSION OF ZIDOVUDINE-RESISTANT HIV-1 [J].
SIEGRIST, CA ;
YERLY, S ;
KAISER, L ;
WYLER, CA ;
PERRIN, L .
LANCET, 1994, 344 (8939-4) :1771-1772
[5]   Rapid, phenotypic HIV-1 drug sensitivity assay for protease and reverse transcriptase inhibitors [J].
Walter, H ;
Schmidt, B ;
Korn, K ;
Vandamme, AM ;
Harrer, T ;
Überla, K .
JOURNAL OF CLINICAL VIROLOGY, 1999, 13 (1-2) :71-80