The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders

被引：386

作者：

Tohen, Mauricio ^{[1
,2
]}

Frank, Ellen ^{[3
]}

Bowden, Charles L.

Colom, Francesc ^{[4
]}

Ghaemi, S. Nassir ^{[5
]}

Yatham, Lakshmi N. ^{[6
]}

Malhi, Gin S. ^{[7
,8
]}

Calabrese, Joseph R. ^{[9
]}

Nolen, Willem A. ^{[10
]}

Vieta, Eduard ^{[4
]}

Kapczinski, Flavio ^{[11
]}

Goodwin, Guy M. ^{[12
]}

Suppes, Trisha ^{[13
]}

Sachs, Gary S. ^{[14
]}

Chengappa, K. N. Roy ^{[3
]}

Grunze, Heinz ^{[15
]}

Mitchell, Philip B. ^{[16
,17
]}

Kanba, Shigenobu ^{[18
]}

Berk, Michael ^{[19
]}

机构：

[1] Univ Texas Hlth Sci Ctr San Antonio, Dept Psychiat, Div Mood & Anxiety Disorders, San Antonio, TX 78229 USA

[2] Harvard Univ, McLean Hosp, Sch Med, Belmont, MA 02178 USA

[3] Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA USA

[4] Univ Barcelona, IDIBAPS, CIBERSAM, Dept Psychiat, Barcelona, Spain

[5] Tufts Univ, Dept Psychiat, Boston, MA 02111 USA

[6] Univ British Columbia, Dept Psychiat, Div Mood Disorders, Vancouver, BC, Canada

[7] Univ Sydney, Dept Psychiat, CADE Clin, Sydney, NSW 2006, Australia

[8] Univ Sydney, Discipline Psychol Med, Sydney, NSW 2006, Australia

[9] Case Western Reserve Univ, Univ Hosp Cleveland, Dept Psychiat, Sch Med, Cleveland, OH 44106 USA

[10] Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, Groningen, Netherlands

[11] Fed Univ, UFRGS, HCPA, INCT Translat Med,Dept Psychiat, Porto Alegre, RS, Brazil

[12] Warneford Hosp, Dept Psychiat, Oxford OX3 7JX, England

[13] Stanford Univ, Dept Psychiat, Palo Alto, CA 94304 USA

[14] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Psychiat, Boston, MA 02114 USA

[15] Newcastle University, Inst Neurosci, Dept Psychiat, Royal Victoria Infirm, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[16] Univ New S Wales, Sch Psychiat, Sydney, NSW, Australia

[17] Black Dog Inst, Sydney, NSW, Australia

[18] Kyushu Univ, Dept Neuropsychiat, Fukuoka, Japan

[19] Univ Melbourne, Dept Clin & Biomed Sci, Melbourne, Vic, Australia

来源：

BIPOLAR DISORDERS | 2009年 / 11卷 / 05期

关键词：

affective switch; bipolar disorder; course and outcome; functional outcome; ISBD; nomenclature; predominant polarity; recovery; recurrence; relapse; remission; response; DEPRESSION RATING-SCALE; PROSPECTIVE FOLLOW-UP; LITHIUM MAINTENANCE TREATMENT; TREATMENT ENHANCEMENT PROGRAM; MONTGOMERY-ASBERG DEPRESSION; CONTROLLED 18-MONTH TRIAL; WEEKLY SYMPTOMATIC STATUS; REPORT QIDS-SR; I DISORDER; FUNCTIONAL IMPAIRMENT;

D O I：

10.1111/j.1399-5618.2009.00726.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objectives: Via an international panel of experts, this paper attempts to document, review, interpret, and propose operational definitions used to describe the course of bipolar disorders for worldwide use, and to disseminate consensus opinion, supported by the existing literature, in order to better predict course and treatment outcomes. Methods: Under the auspices of the International Society for Bipolar Disorders, a task force was convened to examine, report, discuss, and integrate findings from the scientific literature related to observational and clinical trial studies in order to reach consensus and propose terminology describing course and outcome in bipolar disorders. Results: Consensus opinion was reached regarding the definition of nine terms (response, remission, recovery, relapse, recurrence, subsyndromal states, predominant polarity, switch, and functional outcome) commonly used to describe course and outcomes in bipolar disorders. Further studies are needed to validate the proposed definitions. Conclusion: Determination and dissemination of a consensus nomenclature serve as the first step toward producing a validated and standardized system to define course and outcome in bipolar disorders in order to identify predictors of outcome and effects of treatment. The task force acknowledges that there is limited validity to the proposed terms, as for the most part they represent a consensus opinion. These definitions need to be validated in existing databases and in future studies, and the primary goals of the task force are to stimulate research on the validity of proposed concepts and further standardize the technical nomenclature.

引用

页码：453 / 473

页数：21

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