Evolving spinal analgesia practice in palliative care

被引:26
作者
Baker, L [1 ]
Lee, M
Regnard, C
Crack, L
Callin, S
机构
[1] Marie Curie Ctr, Newcastle Upon Tyne NE4 6SS, Tyne & Wear, England
[2] St Oswalds Hospice, Newcastle Upon Tyne, Tyne & Wear, England
关键词
epidural analgesia; intrathecal analgesia; neoplasms; palliative care; spinal injections;
D O I
10.1191/0269216304pm913oa
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Intraspinal analgesia can be helpful in some patients with intractable pain. Over 15 years palliative care professionals evolved their spinals policy through a repeated series of evaluations, discussions and literature reviews. One hundred intraspinal lines were then reviewed. Notable changes in policy were the switch from epidurals to intrathecals, and the insertion of lines during working hours rather than as emergencies. Our efficacy, and frequency of adverse effects, is equal or better to published studies. Key issues in reducing adverse effects were the improved care of the spinal line exit site, a change from bolus administration to continuous infusions, and modifying line insertion techniques. Current policy is to use continuous infusions of diamorphine and bupivacaine in a 1:5 ratio through externalized intrathecal lines. The lines are effective in approximately two thirds of patients and can be kept in place for up to 18 months. The policy continues to be updated and common documentation is now in place.
引用
收藏
页码:507 / 515
页数:9
相关论文
共 72 条
[1]   Long-term outcomes during treatment of chronic pain with intrathecal clonidine or clonidine/opioid combinations [J].
Ackerman, LL ;
Follett, KA ;
Rosenquist, RW .
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 2003, 26 (01) :668-677
[2]  
ANDERSEN PE, 1991, ARCH OTOLARYNGOL, V117, P1277
[3]   Antimicrobial activity of ropivacaine and other local anaesthetics [J].
Aydin, ON ;
Eyigor, M ;
Aydin, N .
EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2001, 18 (10) :687-694
[4]   CHRONIC CANNULATION OF THE INTRADURAL OR EXTRADURAL SPACE IN THE RAT [J].
BAHAR, M ;
ROSEN, M ;
VICKERS, MD .
BRITISH JOURNAL OF ANAESTHESIA, 1984, 56 (04) :405-410
[5]   COST-ANALYSIS OF 2 IMPLANTABLE NARCOTIC DELIVERY SYSTEMS [J].
BEDDER, MD ;
BURCHIEL, K ;
LARSON, A .
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 1991, 6 (06) :368-373
[6]  
BEN J, 1991, REGION ANESTH, V16, P209
[7]   Future directions in the management of pain by intraspinal drug delivery [J].
Bennett, G ;
Deer, T ;
Du Pen, S ;
Rauck, R ;
Yaksh, T ;
Hassenbusch, SJ .
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 2000, 20 (02) :S44-S50
[8]   Evidence-based review of the literature on intrathecal delivery of pain medication [J].
Bennett, G ;
Serafini, M ;
Burchiel, K ;
Buchser, E ;
Classen, A ;
Deer, T ;
Du Pen, S ;
Ferrante, FM ;
Hassenbusch, SJ ;
Lou, L ;
Maeyaert, J ;
Penn, R ;
Portenoy, RK ;
Rauck, R ;
Willis, KD ;
Yaksh, T .
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 2000, 20 (02) :S12-S36
[9]   METABOLISM OF MORPHINE AND HEROIN IN MAN [J].
BOERNER, U ;
ABBOTT, S ;
ROE, RL .
DRUG METABOLISM REVIEWS, 1975, 4 (01) :39-73
[10]  
BURTON M, 1990, NEUROSURGERY, V72, P200