A novel nanogel-based fluorescent probe for ratiometric detection of intracellular pH values

被引：83

作者：

Cao, Lixia ^{[1
]}

Li, Xiaoyan ^{[1
]}

Wang, Shuangqing ^{[1
]}

Li, Shayu ^{[1
]}

Li, Yi ^{[2
]}

Yang, Guoqiang ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, Key Lab Photochem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China

[2] Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Photochem Convers & Optoelect Mat, Beijing 100190, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 63期

基金：

中国国家自然科学基金;

关键词：

CELLS; SENSOR; APOPTOSIS; ESTER;

D O I：

10.1039/c4cc03716b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new nanogel indicator (NGI) for ratiometric fluorescent detection of intracellular pH values has been reported. In aqueous solution, the NGI can be used for ratiometric sensing of pH changes with a large hypsochromic shift of 100 nm in the green-red region and reversible. Furthermore, the NGI has been used to calibrate the cytosol pH value in living cells.

引用

页码：8787 / 8790

页数：4

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