Cytometry, Immunology, and HIV Infection: Three Decades of Strong Interactions

被引：12

作者：

Cossarizza, Andrea ^{[1
]}

De Biasi, Sara ^{[1
]}

Gibellini, Lara ^{[1
]}

Bianchini, Elena ^{[1
]}

Bartolomeo, Regina ^{[1
]}

Nasi, Milena ^{[1
]}

Mussini, Cristina ^{[1
]}

Pinti, Marcello ^{[2
]}

机构：

[1] Univ Modena & Reggio Emilia, Dept Surg Med Dent & Morphol Sci, Modena, Italy

[2] Univ Modena & Reggio Emilia, Dept Life Sci, Modena, Italy

来源：

CYTOMETRY PART A | 2013年 / 83A卷 / 08期

关键词：

HIV; AIDS; cytometry; immune system; CD8(+) T-CELLS; ACTIVE ANTIRETROVIRAL THERAPY; CD1D-RESTRICTED NKT CELLS; MYELOID DENDRITIC CELLS; IMMUNODEFICIENCY-VIRUS HIV; BLOOD MONONUCLEAR-CELLS; MULTIPLEX BEAD ARRAY; NATURAL-KILLER-CELLS; HEPATITIS-C VIRUS; NAIVE B-CELLS;

D O I：

10.1002/cyto.a.22318

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Flow cytometry (FCM) has been extensively used to investigate immunological changes that occur from infection with the human immunodeficiency virus (HIV). This review describes some of the most relevant cellular and molecular changes in the immune system that can be detected by FCM during HIV infection. Finally, it will be discussed how this technology has facilitated the understanding not only of the biology of the virus but also of the mechanisms that the immune system activates to fight HIV and is allowing to monitor the efficacy of antiretroviral therapy. (C) 2013 International Society for Advancement of Cytometry

引用

页码：680 / 691

页数：12

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