The influences of geometric shape of cross section on equilibrium configuration of DNA in elastic rod model

被引:1
作者
Xiao, Ye [1 ]
Huang, Zaixing [1 ]
机构
[1] Nanjing Univ Aeronaut & Astronaut, State Key Lab Mech & Control Mech Struct, Nanjing 210016, Jiangsu, Peoples R China
来源
AIP ADVANCES | 2015年 / 5卷 / 11期
关键词
SUPERCOILED DNA; HELICAL RIBBONS; SINGLE DNA; STABILITY; CHAIN; CURVATURE; MOLECULES; PROTEINS; DYNAMICS; ENERGY;
D O I
10.1063/1.4936639
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
The equilibrium configuration equations of DNA chain with elastic rod model are derived in detail by the variation of the free energy functional, which depends on the curvature, torsion, twisting angle and its derivative with respect to the arc-length of central axis curve of rod. With the different shapes of rod, we obtain the equilibrium equations of DNA with circular and noncircular cross sections, which provide an approach to describe the physical behaviors of A-, B-, Z-DNA. The results show that the elastic rod model with circular cross section can accurately characterize the equilibrium configurations of A-, B-DNA, while the model with elliptical cross sections is more suitable for Z-DNA. (C) 2015 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 Unported License.
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页数:11
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