STROMAL CELLS INHIBIT PANCREATIC TUMOR GROWTH AND ANGIOGENESIS

被引：0
|
作者：
不详
机构：
来源：
CANCER DISCOVERY | 2014年 / 4卷 / 07期
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D O I：
10.1158/2159-8290.CD-RW2014-125
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Major finding: Hedgehog signaling in tumor-associated stromal cells suppresses pancreatic cancer progression. Mechanism: Stromal depletion via Shh inhibition enhances tumor vascularity and accelerates tumor growth. Impact: Patients with poorly differentiated pancreatic tumors may respond to antiangiogenic therapy. © 2014 American Association for Cancer Research.
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页码：758 / 758
页数：1
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