Prognostic value of normal myocardial radionuclide scan in patients with positive treadmill test

The purpose of this study was to determine the prognostic value of a normal 201Tl scan in patients with a positive treadmill exercise stress test. We analyzed retrospectively 85 consecutive patients with a positive treadmill exercise test and normal Tl201 scan who were studied for the diagnosis of coronary artery disease from January 1996 to December 2000. The pretest probability of coronary artery disease was intermediate or high in all patients. Seventy-eight patients (89%) were followed up for 2.03 years. Forty patients (51%) were men. Age was 56 years. The cardiac events considered were angina, revascularization, nonfatal myocardial infarction, and cardiac death. During the follow-up period, none of the patients suffered a major cardiac event. Eight patients had episodes of chest pain and one had angor that required revascularization. Patients with an intermediate probability of coronary artery disease before the test and normal myocardial radionuclide scan had a very good prognosis even with a positive treadmill exercise test.