Multiple familiar trichoepithelioma (Brooke's syndrome). A rare autosomal dermatosis with possible periocular manifestation

被引:0
作者
Rensch, F. [1 ]
Harder, B. [1 ]
Goebeler, M. [2 ]
Back, W. [3 ]
Jonas, J. B. [1 ]
Schlichtenbrede, F. [1 ]
机构
[1] Univ Heidelberg, Med Fak Mannheim, Univ Augenklin, D-68167 Mannheim, Germany
[2] Univ Heidelberg, Med Fak Mannheim, Univ Klin Dermatol Venerol & Allergol, D-68167 Mannheim, Germany
[3] Univ Heidelberg, Med Fak Mannheim, Inst Pathol, D-68167 Mannheim, Germany
来源
OPHTHALMOLOGE | 2009年 / 106卷 / 08期
关键词
Brooke's syndrome; Lid tumor; Trichoepithelioma; Basal cell carcinoma; Hereditary dermatosis; BROOKE-SPIEGLER-SYNDROME; CYLD GENE; CYLINDROMA; CO2-LASER; MUTATION;
D O I
10.1007/s00347-008-1848-2
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Brooke's syndrome is a rare autosomal dominant dermatosis characterized by multiple trichoepitheliomas, which preferentially arise in the face. Therapy consists of excisional surgery of larger tumors and for multiple lesions, dermal abrasion or laser therapy may be considered. Patients with Brooke's syndrome should be closely followed-up due to the possible development of malignant skin tumours. Here, we present a patient with Brooke's syndrome and report on the course of treatment.
引用
收藏
页码:735 / +
页数:4
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