Milk urea nitrogen and infertility in Florida Holstein cows

The objective of this study was to evaluate the association between milk urea nitrogen (MUN) and risk of nonpregnancy after first breeding in a commercial dairy herd in Florida. A total of 515 and 558 cows were classified as having high (17 to 25 mg/dl) or low MUN (6 to 16 mg/dl) within 30 d before first breeding; a total of 158 (30.6%) and 189 (33.8%) cows were diagnosed as pregnant, respectively. Logistic regression was used to evaluate the association between MUN and risk of nonpregnancy controlling for other variables associated with fertility (parity, calving season, breeding season). An interaction was found showing that cows with high MUN that were bred during the summer were 18 times (OR = 17.9; 95% CI = 10.0 to 31.7) at higher risk of nonpregnancy compared to cows with low MUN that were bred during the winter.