Dual Antiplatelet Therapy in Patients with Stable Ischemic Heart Disease

被引：3

作者：

Keach, Joseph Walker ^{[1
,2
]}

Yeh, Robert W. ^{[3
]}

Maddox, Thomas M. ^{[4
,5
,6
]}

机构：

[1] Univ Colorado, Sch Med, Dept Med, Aurora, CO USA

[2] Denver Hlth Hosp Author, Dept Med, Denver, CO USA

[3] Beth Israel Deaconess Med Ctr, Richard A & Susan F Smith Ctr Outcomes Res, Boston, MA 02215 USA

[4] Vet Affairs Eastern Colorado Hlth Care Syst, Cardiol Sect, 1055 Clermont St,Mail Stop 111B, Denver, CO 80220 USA

[5] Univ Colorado, Sch Med, Dept Med Cardiol, Aurora, CO USA

[6] Colorado Cardiovasc Outcomes Res CCOR Consortium, Denver, CO USA

来源：

CURRENT ATHEROSCLEROSIS REPORTS | 2016年 / 18卷 / 01期

关键词：

Coronary artery disease; Stable ischemic heart disease; Dual antiplatelet therapy; Aspirin; Clopidogrel; Ticagrelor; Prasugrel; Myocardial infarction; ELUTING STENT IMPLANTATION; PERCUTANEOUS CORONARY INTERVENTION; OPTIMAL DURATION; METAANALYSIS; CLOPIDOGREL; MORTALITY; ASPIRIN;

D O I：

10.1007/s11883-015-0553-2

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Dual antiplatelet therapy (DAPT) is the use of a P2Y12 receptor antagonist (clopidogrel, prasugrel, or ticagrelor) in combination with aspirin. Recommendations for its use are primarily in patients who have experienced acute coronary syndrome (ACS) or percutaneous coronary intervention (PCI) in the preceding 12 months. There is a growing body of evidence, however, investigating the use of long-duration DAPT in patients with stable ischemic heart disease (SIHD). SIHD is defined as clinical evidence of ischemic heart disease, without an ACS event in the preceding 12 months, and includes patients with stable angina, elective PCI, and remote history of ACS. The use of DAPT in the SIHD population and the recent advancements in our understanding of its use are the focus of this review.

引用

页数：8

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