ENDOSCOPIC LASER SURGERY OF EARLY GLOTTIC CANCER: INVOLVEMENT OF THE ANTERIOR COMMISSURE

被引:96
作者
Roedel, Ralph M. W. [1 ]
Steiner, Wolfgang [1 ]
Mueller, Roland M. [1 ]
Kron, Martina [2 ]
Matthias, Christoph [1 ]
机构
[1] Univ Gottingen, Dept Otorhinolaryngol Head & Neck Surg, Gottingen, Germany
[2] Univ Ulm, Inst Biometr, Ulm, Germany
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2009年 / 31卷 / 05期
关键词
carbon dioxide laser microsurgery; glottic squamous cell carcinoma; early glottic cancer; anterior commissure involvement; local control; SQUAMOUS-CELL CARCINOMA; NEAR-TOTAL LARYNGECTOMY; PARTIAL FRONTOLATERAL LARYNGECTOMY; RADIATION ONCOLOGY CENTERS; CARBON-DIOXIDE LASER; VOCAL CORD CARCINOMA; LOCAL-CONTROL; EPIGLOTTIC RECONSTRUCTION; PROGNOSTIC-FACTORS; FRACTION SIZE;
D O I
10.1002/hed.20993
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background. Early glottic cancer can be cured with transoral laser resection, but in cases with anterior commissure involvement, there is still controversy concerning the best treatment modality. Methods. The impact of anterior commissure involvement on local control was analyzed in a retrospective review of 444 patients with early glottic cancer (pT1a-pT2a) treated between 1986 and 2004 with transoral laser microsurgical resection. Results. The anterior commissure was involved in 153 cases; the 5-year local control rate with and without anterior commissure involvement was 73% versus 89% for T1a and 68% versus 86% for T1b tumors. For T2a lesions, the 5-year local control rate was 76%, irrespective of anterior commissure involvement. Conclusion. In early glottic cancer treated by transoral laser microsurgery, a decrease in local control is evident in case of anterior commissure involvement for T1a and T1b but not for T2a tumors. (C) 2009 Wiley Periodicals, Inc. Head Neck 31: 583-592, 2009
引用
收藏
页码:583 / 592
页数:10
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