Two-photon imaging of a magneto-fluorescent indicator for 3D optical magnetometry

被引：11

作者：

Lee, Hohjai ^{[1
,2
,3
]}

Brinks, Daan ^{[1
,2
]}

Cohen, Adam E. ^{[1
,2
]}

机构：

[1] Harvard Univ, Howard Hughes Med Inst, Dept Chem & Chem Biol & Phys, Cambridge, MA 02138 USA

[2] Harvard Univ, Cambridge, MA 02138 USA

[3] Gwangju Inst Sci & Technol, Dept Chem, Gwangju 61005, South Korea

来源：

OPTICS EXPRESS | 2015年 / 23卷 / 21期

关键词：

MICROSCOPY; MAGNETORECEPTION; NANOPARTICLES; RESOLUTION; PROBE;

D O I：

10.1364/OE.23.028022

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We developed an optical method to visualize the three-dimensional distribution of magnetic field strength around magnetic microstructures. We show that the two-photon-excited fluorescence of a chained donor-bridge-acceptor compound, phenanthrene-(CH2)(12)-O-(CH2)(2)-N, N-dimethylaniline, is sensitive to ambient magnetic field strength. A test structure is immersed in a solution of the magneto-fluorescent indicator and a custom two-photon microscope maps the fluorescence of this compound. The decay kinetics of the electronic excited state provide a measure of magnetic field that is insensitive to photobleaching, indicator concentration, or local variations in optical excitation or collection efficiency. (C) 2015 Optical Society of America

引用

页码：28022 / 28030

页数：9

共 27 条

[11] Medical application of functionalized magnetic nanoparticles [J].