Ionic Liquids and Deep Eutectic Solvents in Natural Products Research: Mixtures of Solids as Extraction Solvents

被引:387
|
作者
Dai, Yuntao [1 ]
van Spronsen, Jaap [2 ]
Witkamp, Geert-Jan [2 ]
Verpoorte, Robert [1 ]
Choi, Young Hae [1 ]
机构
[1] Leiden Univ, Inst Biol, Nat Prod Lab, NL-2300 RA Leiden, Netherlands
[2] Delft Univ Technol, Dept Biotechnol, Delft, Netherlands
来源
JOURNAL OF NATURAL PRODUCTS | 2013年 / 76卷 / 11期
关键词
MICROWAVE-ASSISTED EXTRACTION; SELECTIVE EXTRACTION; CARBON-DIOXIDE; GREEN SOLVENTS; ESSENTIAL OIL; ACID; DISSOLUTION; CELLULOSE; CHLORIDE; C-13;
D O I
10.1021/np400051w
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Mixtures of solid chemicals may become liquid under certain conditions. These liquids are characterized by the formation of strong ionic (ionic liquids) or hydrogen bonds (deep eutectic solvents). Due to their extremely low vapor pressure, they are now widely used in polymer chemistry and synthetic organic chemistry, yet little attention has been paid to their use as extraction solvents of natural products. This review summarizes the preparation of ionic liquids and deep eutectic solvents with natural product components and recent progress in their applications to the extraction and analysis of natural products as well as the recovery of extracted compounds from their extracts. Additionally, various factors affecting extraction features of ionic liquids and deep eutectic solvents, as well as potential useful technologies including microwave and ultrasound to increase the extraction efficiency, are discussed.
引用
收藏
页码:2162 / 2173
页数:12
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