Expression of mycobacterial antigens on murine dissociated Schwann cells infected with Mycobacterium leprae

被引：4

作者：

Birdi, TJ ^{[1
]}

DSouza, S ^{[1
]}

Antia, NH ^{[1
]}

机构：

[1] FDN MED RES,BOMBAY 400018,MAHARASHTRA,INDIA

来源：

MICROBIAL PATHOGENESIS | 1997年 / 22卷 / 03期

基金：

英国惠康基金;

关键词：

mycobacterial antigen; Schwann cells; M-leprae;

D O I：

10.1006/mpat.1996.0101

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mycobacterial antigens were detected in a cell surface ELISA on murine dissociated Schwann cells infected with Mycobacterium leprae. The time kinetics of expression and its refractoriness to modulation with monensin suggests that the antigens are likely to be integrated into the membrane during bacterial entry. This may be partially responsible for the defective Schwann cell functions leading to subsequent peripheral nerve damage. (C) 1997 Academic Press Limited.

引用

页码：181 / 185

页数：5

共 19 条

[1]

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[2]

ANTIA NH, 1985, LEPROSY REV, V56, P331

[3]

ANTIA NH, 1988, INT J LEPROSY, V56, P632

[4]

BJUNE G, 1976, CLIN EXP IMMUNOL, V25, P85