Synthesis of α-chloroamides in water

被引：53

作者：

Harte, Andrew J. ^{[1
]}

Gunnlaugsson, Thorfinnur ^{[1
]}

机构：

[1] Univ Dublin Trinity Coll, Sch Chem, Ctr Synth & Chem Biol, Dublin 2, Ireland

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 35期

关键词：

D O I：

10.1016/j.tetlet.2006.06.090

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction between chloroacetyl chloride and mono- or bis-aliphatic or aromatic amines in water under basic or neutral conditions gives rise to the formation of a variety of functionalized alpha-chloroamides. The resulting products were obtained as solids in moderate to good yields, upon precipitation and isolation by filtration. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：6321 / 6324

页数：4

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